The medication increases the number of blood stem cells in the bloodstream. Peripheral blood stem cell donationįor donation of blood stem cells, donors receive injections of medication that are given under the skin (subcutaneously). Mayo Clinic 2020.After bone marrow collection, donors go to the recovery room, where they are monitored. You're a match: A donor's guide to donation.Clinical trialsĮxplore Mayo Clinic studies of tests and procedures to help prevent, detect, treat or manage conditions. It's difficult to predict the outcome for someone who receives the donation, but it's possible your donation can help save a life. Resultsīecoming a donor is a serious commitment. But most donors can return to their usual activities within days to weeks after donation. Recovery times vary depending on the individual and type of donation. Some donors require multiple apheresis sessions, depending on how many blood stem cells are needed. It is an outpatient procedure that typically takes up to 4 to 6 hours to complete. The blood goes through a machine that takes out the stem cells. The medication is usually started several days before donation.ĭuring the donation, blood is usually taken through a tube (catheter) in a vein in an arm. This process usually takes 1 to 2 hours.Īfter bone marrow collection, donors go to the recovery room, where they are monitored. Needles are inserted through the skin and into the back of the pelvic bone to draw the marrow out of the bone. Anesthesia is used for the procedure to keep donors from feeling pain. What you can expect Bone marrow donationĬollecting stem cells from bone marrow is a type of surgery done in the operating room. The costs related to collecting stem cells for donation are charged to people needing transplants or their health insurance companies. Age 40 is the upper limit for joining the National Marrow Donor Program. Health care providers prefer donors to be ages 18 to 35. The testing helps ensure that the donation will be safe for the donor and recipient.Ĭells from younger donors have the best chance of success when transplanted. A close match increases the chances that the transplant will be a success.ĭonors who are matched with someone who needs a blood stem cell transplant are then tested to make sure they don't have genetic or infectious diseases. This test helps match donors and recipients. HLAs are proteins found in most cells in your body. Next comes testing for human leukocyte antigen (HLA) typing. You'll also be asked to sign a consent form, but you can change your mind at any time. If you want to continue with the process, a blood or tissue sample can be used to help match you to someone who needs a stem cell transplant. If you decide to donate, you'll learn about the process and possible risks of donating. This is a federally funded nonprofit organization that keeps a database of people willing to donate. If you want to donate stem cells, talk to your health care provider or contact the National Marrow Donor Program. Side effects usually disappear within a couple of days after the injections stop. Other possible side effects include being lightheaded or having chills, numbness or tingling around the mouth, and cramping in the hands. The injection that increases the number of stem cells in the blood can cause side effects, such as bone pain, muscle aches, headache, fatigue, nausea and vomiting. The risks of this type of stem cell donation are minimal. But it may take a couple of weeks before you feel fully recovered. You'll likely be able to get back to your routine within a couple of days. Pain relievers such as acetaminophen (Tylenol, others) or ibuprofen (Advil, Motrin IB, others) might help. The surgery might cause tiredness, weakness, and mild back or hip pain. The most serious risk associated with donating bone marrow involves the use and effects of anesthesia during surgery. Bone marrow stem cells are collected from a section of the pelvic bone under general anesthesia.
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